I am a Dek

Esclerosis Focal Segmentaria – Es una lesión no un diagnóstico – Fisiopatología: Podocitopatía – Formas primarias dan lugar a secundarias – Grandes avances. Spanish, Glomeruloesclerosis Focal y Segmentaria, Glomeruloesclerosis focal y Glomerulosclerosis Segmentaria y Focal, esclerosis glomerular focal. Resumen. SEGARRA-MEDRANO, Alfonso et al. Treatment of idiopathic focal segmental glomerulosclerosis: options in the event of resistance to corticosteroids.

Author: Grozilkree Akiktilar
Country: Seychelles
Language: English (Spanish)
Genre: Life
Published (Last): 21 February 2004
Pages: 15
PDF File Size: 3.45 Mb
ePub File Size: 10.23 Mb
ISBN: 252-9-26152-358-8
Downloads: 8034
Price: Free* [*Free Regsitration Required]
Uploader: Bagal

Presence of urokinase-type plasminogen activator receptor in urine of cancer patients and its possible clinical relevance.

See Case 6 – Case 40 – Case 86 of our case series. Soluble urokinase plasminogen activator receptor is a marker of dysmetabolism in HIV-infected patients receiving highly active antiretroviral therapy. There is predilection by Afro-American patients.

The ligand-binding domain of the cell surface receptor for urokinase-type plasminogen activator.

Focal segmental glomerulosclerosis (FSGS) – Symptoms and causes – Mayo Clinic

The degree of tubulointerstitial damage varies from case to case and appears more pronounced in those forms where intrinsic epithelial cell damage, such as viral infection, is the related factor Albaqumi M, Barisoni L. All seven patients discontinued anabolic steroids, leading to weight loss, stabilization or improvement in serum creatinine, and a reduction in proteinuria.

Mayo Foundation for Medical Education and Research; Most of these proteins are essential for a functional slit diaphragm and glomerular filtration, since mutation or inactivation of the corresponding genes causes proteinuria.


Segmental Hyalinosis with lipid vacuoles and reddish color with the trichrome stain arrow. Email al autor Se requiere ingresas a sistema.

Una causa poco frecuente de diarrea en pacientes con glomeruloesclerosis focal y segmentaria. Some authors consider that hyaline lesions are precursory of those sclerosing; nevertheless, seems that in many cases sclerosing lesions begins thus, without a phase of hyalinosis.

Focal segmental glomerulosclerosis

There are at least 6 mutations in this channel, located throughout the channel. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years. Clinical follow-up and home visit were performed in 44 patients The coexistence of these two diseases is an unexpected condition.

In the case of corticosteroid resistance, the best evidence-based option has classically been treatment with calcineurin inhibitors, although recent studies indicate that mycophenolate may have similar efficacy. Rituximab targets podocytes in recurrent focal segmental glomerulosclerosis. A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary.

It is possible that these deposits do not represent immune complexes nor they are pathogenic and that they are the result of unspecific deposition of serum proteins. You can change the settings or obtain more information by clicking here.

Focal segmental glomerulosclerosis – Wikipedia

There can be mesangial hypercellularity, podocyte hypertrophy-hyperplasia, or glomerulomegaly. Defining criteria include both of the following: Peritubular capillaries yy rarefied in congenital nephrotic syndrome of the Finnish type.


Direct immunofluorescence with antibodies anti-IgM, marked with fluorescein, X Diseases of ion channels. Nevertheless, these same authors propose, in a very interesting work, that the human serum could contain factors that are crucial for development and normal distribution of these proteins of the complex: Advances in the biology and genetics of the podocytopathies: D ICD – The role of parietal epithelial cells PECs has been highlighted.

A suPAR circulating factor causes kidney disease.

RQ is a common disease-associated allele”. Primary focal segmental glomerulosclerosis–long-term outcome after pediatric renal transplantation.

Glomeruloesclerosis Focal y Segmentaria en el Adulto

Studies with more cases and longer follow-up are focwl to segmentarix its impact on preservation of kidney function. Nephrotic focal segmental glomerulosclerosis in NPHS2 that codifies another exclusive protein of the podocyte: In other words, if there are many glomeruli with perihilar lesions, but at least one with hypercellular or collapsing lesion, we do not diagnose the perihilar variant, but like these last ones respectively.

Descargar ppt “Glomeruloesclerosis Focal y Segmentaria en el Adulto”. The number of affected glomeruli is very variable.